RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Tnf
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Immunofluorescence; qRT-PCR; Western Blot etc.
Target
NA
Pathway
NA
PubMed ID
Title
GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro
Year
2021
Function
"Firstly, we found that the lung expression levels of Tnf (the gene encoding TNF-alfa) and Il1b (the gene encoding IL-1beta) were higher in BLM-treated mice than in control animals."